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Transcription Factor Binding Site Prediction

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690 ChIP-seq

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Papers

GenomeQA: Benchmarking General Large Language Models for Genome Sequence Understanding

2026-04-07 · Weicai Long, Yusen Hou, Junning Feng, Houcheng Su 외 arxiv

Large Language Models (LLMs) are increasingly adopted as conversational assistants in genomics, where they are mainly used to reason over biological knowledge, annotations, and analysis outputs through natural language i…

Transcription Factor Binding Site Prediction

Explainable AI in Genomics: Transcription Factor Binding Site Prediction with Mixture of Experts

2025-07-13 · Aakash Tripathi, Ian E. Nielsen, Muhammad Umer, Ravi P. Ramachandran 외 arxiv

Transcription Factor Binding Site (TFBS) prediction is crucial for understanding gene regulation and various biological processes. This study introduces a novel Mixture of Experts (MoE) approach for TFBS prediction, inte…

Transcription Factor Binding Site Prediction

GCBLANE: A graph-enhanced convolutional BiLSTM attention network for improved transcription factor binding site prediction

2025-03-16 · Jonas Chris Ferrao, Dickson Dias, Sweta Morajkar, Manisha Gokuldas Fal Dessai

Identifying transcription factor binding sites (TFBS) is crucial for understanding gene regulation, as these sites enable transcription factors (TFs) to bind to DNA and modulate gene expression. Despite advances in high-…

Graph Neural NetworkTranscription Factor Binding Site Prediction

DNABERT-2: Efficient Foundation Model and Benchmark For Multi-Species Genome

2023-06-26 · Zhihan Zhou, Yanrong Ji, Weijian Li, Pratik Dutta 외

Decoding the linguistic intricacies of the genome is a crucial problem in biology, and pre-trained foundational models such as DNABERT and Nucleotide Transformer have made significant strides in this area. Existing works…

Computational EfficiencyCore Promoter DetectionCovid Variant PredictionData Compression+9

Convolutional Kitchen Sinks for Transcription Factor Binding Site Prediction

2017-05-31

We present a simple and efficient method for prediction of transcription factor binding sites from DNA sequence. Our method computes a random approximation of a convolutional kernel feature map from DNA sequence and then…

PredictionTranscription Factor Binding Site Prediction