@article{beyondaffinityabenchmarkof1d2dand3dmetho,
  title = {Beyond Affinity: A Benchmark of 1D, 2D, and 3D Methods Reveals Critical Trade-offs in Structure-Based Drug Design},
  author = {Kangyu Zheng and Kai Zhang and Jiale Tan and Xuehan Chen and Yingzhou Lu and Zaixi Zhang and Lichao Sun and Marinka Zitnik and Tianfan Fu and Zhiding Liang},
  year = {2026},
  eprint = {2601.14283},
  archivePrefix = {arXiv},
  url = {https://arxiv.org/abs/2601.14283},
}