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AI-Augmented Thyroid Scintigraphy for Robust Classification

2025-03-01 · Maziar Sabouri, Ghasem Hajianfar, Alireza Rafiei Sardouei, Milad Yazdani, Azin Asadzadeh, Soroush Bagheri, Mohsen Arabi, Seyed Rasoul Zakavi, Emran Askari, Atena Aghaee, Dena Shahriari, Habib Zaidi, Arman Rahmim

Thyroid scintigraphy is a key imaging modality for diagnosing thyroid disorders. Deep learning models for thyroid scintigraphy classification often face challenges due to limited and imbalanced datasets, leading to suboptimal generalization. In this study, we investigate the effectiveness of different data augmentation techniques including Stable Diffusion (SD), Flow Matching (FM), and Conventional Augmentation (CA) to enhance the performance of a ResNet18 classifier for thyroid condition classification. Our results showed that FM-based augmentation consistently outperforms SD-based approaches, particularly when combined with original (O) data and CA (O+FM+CA), achieving both high accuracy and fair classification across Diffuse Goiter (DG), Nodular Goiter (NG), Normal (NL), and Thyroiditis (TI) cases. The Wilcoxon statistical analysis further validated the superiority of O+FM and its variants (O+FM+CA) over SD-based augmentations in most scenarios. These findings highlight the potential of FM-based augmentation as a superior approach for generating high-quality synthetic thyroid scintigraphy images and improving model generalization in medical image classification.

📄 PDF Abstract BibTeX arXiv:2503.00366

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ClassificationData Augmentationimage-classificationImage ClassificationMedical Image ClassificationRobust classification

Methods 이 논문이 사용한 방법론

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