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A comparative study between vision transformers and CNNs in digital pathology

2022-06-01 · Luca Deininger, Bernhard Stimpel, Anil Yuce, Samaneh Abbasi-Sureshjani, Simon Schönenberger, Paolo Ocampo, Konstanty Korski, Fabien Gaire

Recently, vision transformers were shown to be capable of outperforming convolutional neural networks when pretrained on sufficient amounts of data. In comparison to convolutional neural networks, vision transformers have a weaker inductive bias and therefore allow a more flexible feature detection. Due to their promising feature detection, this work explores vision transformers for tumor detection in digital pathology whole slide images in four tissue types, and for tissue type identification. We compared the patch-wise classification performance of the vision transformer DeiT-Tiny to the state-of-the-art convolutional neural network ResNet18. Due to the sparse availability of annotated whole slide images, we further compared both models pretrained on large amounts of unlabeled whole-slide images using state-of-the-art self-supervised approaches. The results show that the vision transformer performed slightly better than the ResNet18 for three of four tissue types for tumor detection while the ResNet18 performed slightly better for the remaining tasks. The aggregated predictions of both models on slide level were correlated, indicating that the models captured similar imaging features. All together, the vision transformer models performed on par with the ResNet18 while requiring more effort to train. In order to surpass the performance of convolutional neural networks, vision transformers might require more challenging tasks to benefit from their weak inductive bias.

📄 PDF Abstract BibTeX arXiv:2206.00389

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Inductive Biaswhole slide images

Methods 이 논문이 사용한 방법론

Attention 설명 없음
Linear Layer A Linear Layer is a projection $\mathbf{XW + b}$.
Softmax The Softmax output function transforms a previous layer's output into a vector of probabilities. It is commonly used for multiclass classification. Given an input vector $x$…
Multi-Head Attention 설명 없음
Residual Connection 설명 없음
Layer Normalization Unlike batch normalization, Layer Normalization directly estimates the normalization statistics from the summed inputs…
Dense Connections Dense Connections, or Fully Connected Connections, are a type of layer in a deep neural network that use a linear operation where every input is connected to every output…
Vision Transformer The Vision Transformer, or ViT, is a model for image classification that employs a Transformer-like architecture over…

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