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A optimization framework for herbal prescription planning based on deep reinforcement learning

2023-04-25 · Kuo Yang, Zecong Yu, Xin Su, Xiong He, Ning Wang, Qiguang Zheng, Feidie Yu, Zhuang Liu, Tiancai Wen, Xuezhong Zhou

Treatment planning for chronic diseases is a critical task in medical artificial intelligence, particularly in traditional Chinese medicine (TCM). However, generating optimized sequential treatment strategies for patients with chronic diseases in different clinical encounters remains a challenging issue that requires further exploration. In this study, we proposed a TCM herbal prescription planning framework based on deep reinforcement learning for chronic disease treatment (PrescDRL). PrescDRL is a sequential herbal prescription optimization model that focuses on long-term effectiveness rather than achieving maximum reward at every step, thereby ensuring better patient outcomes. We constructed a high-quality benchmark dataset for sequential diagnosis and treatment of diabetes and evaluated PrescDRL against this benchmark. Our results showed that PrescDRL achieved a higher curative effect, with the single-step reward improving by 117% and 153% compared to doctors. Furthermore, PrescDRL outperformed the benchmark in prescription prediction, with precision improving by 40.5% and recall improving by 63%. Overall, our study demonstrates the potential of using artificial intelligence to improve clinical intelligent diagnosis and treatment in TCM.

📄 PDF Abstract BibTeX arXiv:2304.12828

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Deep Reinforcement Learningreinforcement-learningSequential Diagnosis

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