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Adversarial Examples for DNA Classification

2024-09-29 · Hyunwoo Yoo

Pre-trained language models such as DNABERT2 and Nucleotide Transformer, which are trained on DNA sequences, have shown promising performance in DNA sequence classification tasks. The classification ability of these models stems from language models trained on vast amounts of DNA sequence samples, followed by fine-tuning with relatively smaller classification datasets. However, these text-based systems are not robust enough and can be vulnerable to adversarial examples. While adversarial attacks have been widely studied in text classification, there is limited research in DNA sequence classification. In this paper, we adapt commonly used attack algorithms in text classification for DNA sequence classification. We evaluated the impact of various attack methods on DNA sequence classification at the character, word, and sentence levels. Our findings indicate that actual DNA language model sequence classifiers are vulnerable to these attacks.

📄 PDF Abstract BibTeX arXiv:2409.19788

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Tasks

ClassificationLanguage ModelingLanguage ModellingSentencetext-classificationText Classification

Methods 이 논문이 사용한 방법론

Linear Layer A Linear Layer is a projection $\mathbf{XW + b}$.
Multi-Head Attention 설명 없음
Layer Normalization Unlike batch normalization, Layer Normalization directly estimates the normalization statistics from the summed inputs…
Dense Connections Dense Connections, or Fully Connected Connections, are a type of layer in a deep neural network that use a linear operation where every input is connected to every output…
Attention 설명 없음
Adam 설명 없음
Residual Connection 설명 없음
Position-Wise Feed-Forward Layer 설명 없음

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