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Benchmarking PathCLIP for Pathology Image Analysis

2024-01-05 · Sunyi Zheng, Xiaonan Cui, Yuxuan Sun, Jingxiong Li, Honglin Li, Yunlong Zhang, Pingyi Chen, Xueping Jing, Zhaoxiang Ye, Lin Yang

Accurate image classification and retrieval are of importance for clinical diagnosis and treatment decision-making. The recent contrastive language-image pretraining (CLIP) model has shown remarkable proficiency in understanding natural images. Drawing inspiration from CLIP, PathCLIP is specifically designed for pathology image analysis, utilizing over 200,000 image and text pairs in training. While the performance the PathCLIP is impressive, its robustness under a wide range of image corruptions remains unknown. Therefore, we conduct an extensive evaluation to analyze the performance of PathCLIP on various corrupted images from the datasets of Osteosarcoma and WSSS4LUAD. In our experiments, we introduce seven corruption types including brightness, contrast, Gaussian blur, resolution, saturation, hue, and markup at four severity levels. Through experiments, we find that PathCLIP is relatively robustness to image corruptions and surpasses OpenAI-CLIP and PLIP in zero-shot classification. Among the seven corruptions, blur and resolution can cause server performance degradation of the PathCLIP. This indicates that ensuring the quality of images is crucial before conducting a clinical test. Additionally, we assess the robustness of PathCLIP in the task of image-image retrieval, revealing that PathCLIP performs less effectively than PLIP on Osteosarcoma but performs better on WSSS4LUAD under diverse corruptions. Overall, PathCLIP presents impressive zero-shot classification and retrieval performance for pathology images, but appropriate care needs to be taken when using it. We hope this study provides a qualitative impression of PathCLIP and helps understand its differences from other CLIP models.

📄 PDF Abstract BibTeX arXiv:2401.02651

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Tasks

BenchmarkingDecision Makingimage-classificationImage ClassificationImage RetrievalRetrievalzero-shot-classificationZero-Shot Learning

Methods 이 논문이 사용한 방법론

PLIP Pathology Language and Image Pre-Training (PLIP) is a vision-and-language foundation model created by fine-tuning CLIP on pathology images.
CLIP Contrastive Language-Image Pre-training (CLIP), consisting of a simplified version of ConVIRT trained from scratch, is an efficient method of image representation learning…

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