Bimodal Distribution Removal and Genetic Algorithm in Neural Network for Breast Cancer Diagnosis
Diagnosis of breast cancer has been well studied in the past. Multiple linear programming models have been devised to approximate the relationship between cell features and tumour malignancy. However, these models are less capable in handling non-linear correlations. Neural networks instead are powerful in processing complex non-linear correlations. It is thus certainly beneficial to approach this cancer diagnosis problem with a model based on neural network. Particularly, introducing bias to neural network training process is deemed as an important means to increase training efficiency. Out of a number of popular proposed methods for introducing artificial bias, Bimodal Distribution Removal (BDR) presents ideal efficiency improvement results and fair simplicity in implementation. However, this paper examines the effectiveness of BDR against the target cancer diagnosis classification problem and shows that BDR process in fact negatively impacts classification performance. In addition, this paper also explores genetic algorithm as an efficient tool for feature selection and produced significantly better results comparing to baseline model that without any feature selection in place
Code (0)
등록된 구현이 없습니다.
Tasks
feature selectionGeneral ClassificationMethods 이 논문이 사용한 방법론
Similar Papers 제목 키워드 기반
Genetic Toggle Switch in the Absence of Cooperative Binding: Exact Results
We present an analytical treatment of a genetic switch model consisting of two mutually inhibiting genes operating without cooperative binding of the corresponding transcription factors. Previous studies have numerically…
Deep neural network improves the estimation of polygenic risk scores for breast cancer
Polygenic risk scores (PRS) estimate the genetic risk of an individual for a complex disease based on many genetic variants across the whole genome. In this study, we compared a series of computational models for estimat…
Automatic Mammogram image Breast Region Extraction and Removal of Pectoral Muscle
Currently Mammography is a most effective imaging modality used by radiologists for the screening of breast cancer. Finding an accurate, robust and efficient breast region segmentation technique still remains a challengi…
A Deep Embedded Refined Clustering Approach for Breast Cancer Distinction based on DNA Methylation
Epigenetic alterations have an important role in the development of several types of cancer. Epigenetic studies generate a large amount of data, which makes it essential to develop novel models capable of dealing with la…
Cancer ClassificationClusteringDimensionality ReductionGeneral ClassificationIdentifying Epigenetic Signature of Breast Cancer with Machine Learning
The research reported in this paper identifies the epigenetic biomarker (methylation beta pattern) of breast cancer. Many cancers are triggered by abnormal gene expression levels caused by aberrant methylation of CpG sit…
BIG-bench Machine Learning