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Coping with seasons: evolutionary dynamics of gene networks in a changing environment

2023-07-04 · Csenge Petak, Lapo Frati, Melissa H. Pespeni, Nick Cheney

In environments that vary frequently and unpredictably, bet-hedgers can overtake the population. Diversifying bet-hedgers have a diverse set of offspring so that, no matter the conditions they find themselves in, at least some offspring will have high fitness. In contrast, conservative bet-hedgers have a set of offspring that all have an in-between phenotype compared to the specialists. Here, we use an evolutionary algorithm of gene regulatory networks to de novo evolve the two strategies and investigate their relative success in different parameter settings. We found that diversifying bet-hedgers almost always evolved first, but then eventually got outcompeted by conservative bet-hedgers. We argue that even though similar selection pressures apply to the two bet-hedger strategies, conservative bet-hedgers could win due to the robustness of their evolved networks, in contrast to the sensitive networks of the diversifying bet-hedgers. These results reveal an unexplored aspect of the evolution of bet-hedging that could shed more light on the principles of biological adaptation in variable environmental conditions.

📄 PDF Abstract BibTeX arXiv:2307.01602

Code (1)

cpetak/coping_with_seasons_grn 공식 구현 pytorch

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