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Deep Learning-Driven Segmentation of Ischemic Stroke Lesions Using Multi-Channel MRI

2025-01-04 · Ashiqur Rahman, Muhammad E. H. Chowdhury, Md Sharjis Ibne Wadud, Rusab Sarmun, Adam Mushtak, Sohaib Bassam Zoghoul, Israa Al-Hashimi

Ischemic stroke, caused by cerebral vessel occlusion, presents substantial challenges in medical imaging due to the variability and subtlety of stroke lesions. Magnetic Resonance Imaging (MRI) plays a crucial role in diagnosing and managing ischemic stroke, yet existing segmentation techniques often fail to accurately delineate lesions. This study introduces a novel deep learning-based method for segmenting ischemic stroke lesions using multi-channel MRI modalities, including Diffusion Weighted Imaging (DWI), Apparent Diffusion Coefficient (ADC), and enhanced Diffusion Weighted Imaging (eDWI). The proposed architecture integrates DenseNet121 as the encoder with Self-Organized Operational Neural Networks (SelfONN) in the decoder, enhanced by Channel and Space Compound Attention (CSCA) and Double Squeeze-and-Excitation (DSE) blocks. Additionally, a custom loss function combining Dice Loss and Jaccard Loss with weighted averages is introduced to improve model performance. Trained and evaluated on the ISLES 2022 dataset, the model achieved Dice Similarity Coefficients (DSC) of 83.88% using DWI alone, 85.86% with DWI and ADC, and 87.49% with the integration of DWI, ADC, and eDWI. This approach not only outperforms existing methods but also addresses key limitations in current segmentation practices. These advancements significantly enhance diagnostic precision and treatment planning for ischemic stroke, providing valuable support for clinical decision-making.

📄 PDF Abstract BibTeX arXiv:2501.02287

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Diagnostic

Methods 이 논문이 사용한 방법론

Softmax The Softmax output function transforms a previous layer's output into a vector of probabilities. It is commonly used for multiclass classification. Given an input vector $x$…
Attention 설명 없음
Diffusion Diffusion models generate samples by gradually removing noise from a signal, and their training objective can be expressed as a reweighted variational lower-bound…
Dice Loss \begin{equation} DiceLoss\left( y, \overline{p} \right) = 1 - \dfrac{\left( 2y\overline{p} + 1 \right)} {\left( y+\overline{p } + 1 \right)} \end{equation}

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