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Dual-domain Multi-path Self-supervised Diffusion Model for Accelerated MRI Reconstruction

2025-03-24 · Yuxuan Zhang, Jinkui Hao, Bo Zhou

Magnetic resonance imaging (MRI) is a vital diagnostic tool, but its inherently long acquisition times reduce clinical efficiency and patient comfort. Recent advancements in deep learning, particularly diffusion models, have improved accelerated MRI reconstruction. However, existing diffusion models' training often relies on fully sampled data, models incur high computational costs, and often lack uncertainty estimation, limiting their clinical applicability. To overcome these challenges, we propose a novel framework, called Dual-domain Multi-path Self-supervised Diffusion Model (DMSM), that integrates a self-supervised dual-domain diffusion model training scheme, a lightweight hybrid attention network for the reconstruction diffusion model, and a multi-path inference strategy, to enhance reconstruction accuracy, efficiency, and explainability. Unlike traditional diffusion-based models, DMSM eliminates the dependency on training from fully sampled data, making it more practical for real-world clinical settings. We evaluated DMSM on two human MRI datasets, demonstrating that it achieves favorable performance over several supervised and self-supervised baselines, particularly in preserving fine anatomical structures and suppressing artifacts under high acceleration factors. Additionally, our model generates uncertainty maps that correlate reasonably well with reconstruction errors, offering valuable clinically interpretable guidance and potentially enhancing diagnostic confidence.

📄 PDF Abstract BibTeX arXiv:2503.18836

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Tasks

DiagnosticMRI Reconstruction

Methods 이 논문이 사용한 방법론

Softmax The Softmax output function transforms a previous layer's output into a vector of probabilities. It is commonly used for multiclass classification. Given an input vector $x$…
Attention 설명 없음
Diffusion Diffusion models generate samples by gradually removing noise from a signal, and their training objective can be expressed as a reweighted variational lower-bound…

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