How oscillations in SIRS epidemic models are affected by the distribution of immunity times
Models for resident infectious diseases, like the SIRS model, may settle into an endemic state with constant numbers of susceptible ($S$), infected ($I$) and recovered ($R$) individuals, where recovered individuals attain a temporary immunity to reinfection. For many infectious pathogens, infection dynamics may also show periodic outbreaks corresponding to a limit cycle in phase space. One way to reproduce oscillations in SIRS models is to include a non-exponential dwell-time distribution in the recovered state. Here, we study a SIRS model with a step-function-like kernel for the immunity time, mapping out the model's full phase diagram. Using the kernel series framework, we are able to identify the onset of periodic outbreaks when successively broadening the step-width. We further investigate the shape of the outbreaks, finding that broader steps cause more sinusoidal oscillations while more uniform immunity time distributions are related to sharper outbreaks occurring after extended periods of low infection activity. Our main results concern recovery distributions characterized by a single dominant timescale. We also consider recovery distributions with two timescales, which may be observed when two or more distinct recovery processes co-exist. Surprisingly, two qualitatively different limit cycles are found to be stable in this case, with only one of the two limit cycles emerging via a standard supercritical Hopf bifurcation.
Code (0)
등록된 구현이 없습니다.
Similar Papers 제목 키워드 기반
Extending SIRS epidemics to allow for gradual waning of immunity
SIRS epidemic models assume that individual immunity (from infection and vaccination) wanes in one big leap, from complete immunity to complete susceptibility. For many diseases immunity on the contrary wanes gradually, …
SIRS epidemics with individual heterogeneity of immunity waning
We analyse an extended SIRS epidemic model in which immunity at the individual level wanes gradually at exponential rate, but where the waning rate may differ between individuals, for instance as an effect of differences…
A new oscillatory regime in two-strain epidemic models with partial cross-immunity
Infectious diseases often involve multiple strains that interact through the immune response generated after an infection. This study investigates the conditions under which a two-strain epidemic model with partial cross…
Endemic Oscillations for SARS-CoV-2 Omicron -- A SIRS model analysis
The SIRS model with constant vaccination and immunity waning rates is well known to show a transition from a disease-free to an endemic equilibrium as the basic reproduction number $r_0$ is raised above threshold. It is …
A simple model of epidemic dynamics with memory effects
We introduce a modified SIR model with memory for the dynamics of epidemic spreading in a constant population of individuals. Each individual is in one of the states susceptible (${\bf S}$), infected (${\bf I}$) or recov…