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Measures and Models of Brain-Heart Interactions

2024-09-24 · Diego Candia-Rivera, Luca Faes, Fabrizio De Vico Fallani, Mario Chavez

The exploration of brain-heart interactions within various paradigms, including affective computing, human-computer interfaces, and sensorimotor evaluation, stands as a significant milestone in biomarker development and neuroscientific research. A range of techniques, spanning from molecular to behavioral approaches, has been proposed to measure these interactions. Different frameworks use signal processing techniques, from the estimation of brain responses to individual heartbeats to higher-order dynamics linking cardiac inputs to changes in brain organization. This review provides an overview to the most notable signal processing strategies currently used for measuring and modeling brain-heart interactions. It discusses their usability and highlights the main challenges that need to be addressed for future methodological developments. Current methodologies have deepened our understanding of the impact of neural disruptions on brain-heart interactions, solidifying it as a biomarker for evaluation of the physiological state of the nervous system and holding immense potential for disease stratification. The vast outlook of these methods becomes apparent specially in neurological and psychiatric disorders. As we tackle new methodological challenges, gaining a more profound understanding of how these interactions operate, we anticipate further insights into the role of peripheral neurons and the environmental input from the rest of the body in shaping brain functioning.

📄 PDF Abstract BibTeX arXiv:2409.15835

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