Model predictive control for the prescription of antithyroid agents
Although hyperthyroidism is a common disease, the pharmaceutical therapy is based on a trial-and-error approach. We extend a mathematical model of the pituitary-thyroid feedback loop such that the intake of one antithyroid agent, namely methimazole (MMI), can be considered and use a model predictive control (MPC) scheme to determine suitable dosages.
Code (0)
등록된 구현이 없습니다.
Tasks
Model Predictive ControlSimilar Papers 제목 키워드 기반
Modeling and Predictive Control for the Treatment of Hyperthyroidism
In this work, we propose an approach to determine the dosages of antithyroid agents to treat hyperthyroid patients. Instead of relying on a trial-and-error approach as it is commonly done in clinical practice, we suggest…
Model Predictive ControlLeveraging Evolutionary Surrogate-Assisted Prescription in Multi-Objective Chlorination Control Systems
This short, written report introduces the idea of Evolutionary Surrogate-Assisted Prescription (ESP) and presents preliminary results on its potential use in training real-world agents as a part of the 1st AI for Drinkin…
Integrated Optimization of Predictive and Prescriptive Tasks
In traditional machine learning techniques, the degree of closeness between true and predicted values generally measures the quality of predictions. However, these learning algorithms do not consider prescription problem…
BIG-bench Machine LearningBilevel OptimizationStochastic OptimizationDiscovering heterogeneous subpopulations for fine-grained analysis of opioid use and opioid use disorders
The opioid epidemic in the United States claims over 40,000 lives per year, and it is estimated that well over two million Americans have an opioid use disorder. Over-prescription and misuse of prescription opioids play …
Medical DiagnosisGA-SVM for Evaluating Heroin Consumption Risk
There were over 70,000 drug overdose deaths in the USA in 2017. Almost half of those involved the use of Opioids such as Heroin. This research supports efforts to combat the Opioid Epidemic by further understanding facto…