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Ontology- and LLM-based Data Harmonization for Federated Learning in Healthcare

2025-05-26 · Natallia Kokash, Lei Wang, Thomas H. Gillespie, Adam Belloum, Paola Grosso, Sara Quinney, Lang Li, Bernard de Bono

The rise of electronic health records (EHRs) has unlocked new opportunities for medical research, but privacy regulations and data heterogeneity remain key barriers to large-scale machine learning. Federated learning (FL) enables collaborative modeling without sharing raw data, yet faces challenges in harmonizing diverse clinical datasets. This paper presents a two-step data alignment strategy integrating ontologies and large language models (LLMs) to support secure, privacy-preserving FL in healthcare, demonstrating its effectiveness in a real-world project involving semantic mapping of EHR data.

📄 PDF Abstract BibTeX arXiv:2505.20020

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Federated LearningPrivacy Preserving

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