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Position: AI Will Transform Neuropsychology Through Mental Health Digital Twins for Dynamic Mental Health Care, Especially for ADHD

2025-10-08 · Neil Natarajan, Sruthi Viswanathan, Xavier Roberts-Gaal, Michelle Marie Martel arxiv

Static solutions don't serve a dynamic mind. Thus, we advocate a shift from static mental health diagnostic assessments to continuous, artificial intelligence (AI)-driven assessment. Focusing on Attention-Deficit/Hyperactivity Disorder (ADHD) as a case study, we explore how generative AI has the potential to address current capacity constraints in neuropsychology, potentially enabling more personalized and longitudinal care pathways. In particular, AI can efficiently conduct frequent, low-level experience sampling from patients and facilitate diagnostic reconciliation across care pathways. We envision a future where mental health care benefits from continuous, rich, and patient-centered data sampling to dynamically adapt to individual patient needs and evolving conditions, thereby improving both accessibility and efficacy of treatment. We further propose the use of mental health digital twins (MHDTs) - continuously updated computational models that capture individual symptom dynamics and trajectories - as a transformative framework for personalized mental health care. We ground this framework in empirical evidence and map out the research agenda required to refine and operationalize it.

📄 PDF Abstract BibTeX arXiv:2510.07409

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