Pyroptosis: Physiological roles in viral infection
The current review focuses on important aspects of pyroptosis, such as morphological features of inflammasomes, as well as on knowledge about coronavirus infection mechanisms and the association between SARS-CoV-2 infection and cell pyroptosis. The application of immunomodulation therapies to Covid-19 patients is the most promising treatment under investigation nowadays. The possibilities of assistance to help protecting patients from infections are also addressed in the present study.
Code (0)
등록된 구현이 없습니다.
Similar Papers 제목 키워드 기반
Multi-point Infection Dynamics of Hepatitis B in the Presence of Sub-Viral Particles
Hepatitis B virus (HBV) is considered as etiological agent of the lethal liver disease hepatitis B. Globally, hepatitis B is recognized as one of the prevailing infectious diseases with a significant impact on human heal…
Antigenic cooperation in Viral Populations: Transformation of Functions of Intra-Host Viral Variants
In this paper we study intra-host viral adaptation by antigenic cooperation - a mechanism of immune escape that serves as an alternative to the standard mechanism of escape by continuous genomic diversification and allow…
Viral Dark Matter: Illuminating Protein Function, Ecology, and Biotechnological Promises
Viruses are the most abundant biological entities on Earth and play central roles in shaping microbiomes and influencing ecosystem functions. Yet, most viral genes remain uncharacterized, comprising what is commonly refe…
Inheritance of intracellular viral RNA in a multiscale model of hepatitis C infection
Multiscale mathematical models of hepatitis C infection have been instrumental in our understanding of direct acting antivirals. These models include the mechanisms driving intracellular viral production and explicitly m…
Predictability of viral load dynamics in the early phases of SARS-CoV-2 through a model-based approach
A pipeline to evaluate the evolution of viral dynamics based on a new model-driven approach has been developed in the present study. The proposed methods exploit real data and the multiscale structure of the infection dy…