paper-with-me

홈 › Papers

Reinforcement Learning for Evidence-Seeking Diagnostic Reasoning with Large Language Models

2026-07-03 · Shengyi Hua, Kangzhe Hu, Conghui He, Xiaofan Zhang, Shaoting Zhang arxiv

Recent reasoning-centric Large Language Models (LLMs) have made significant strides, yet they predominantly operate on a passive-inference pattern that assumes complete information. In contrast, real-world clinical intelligence is inherently an iterative investigative process requiring strategic evidence acquisition. To bridge this gap, we formalize medical diagnosis as an Iterative Evidence-Seeking Task. We leverage Reinforcement Learning with Verifiable Rewards (RLVR) to elicit intrinsic reasoning within a closed-loop environment, guided by a novel suite of rewards that enforce diagnostic precision and examination consistency. To facilitate this, we introduce the Retrieval-Augmented Generation-based Examination Simulator (RAGES), a high-fidelity clinical oracle that provides realistic, knowledge-grounded follow-up evidence. Empirical results across diverse datasets demonstrate that our framework enables LLMs to transition from passive responders to autonomous assistants. Notably, our model demonstrates comparable performance to larger and reasoning-enhanced baselines, while RAGES proves superior to vanilla LLMs in generating biologically plausible clinical feedback.

📄 PDF Abstract BibTeX arXiv:2607.02983

Code (0)

등록된 구현이 없습니다.

Tasks

Reinforcement LearningMedical Diagnosis

Similar Papers 제목 키워드 기반

PathFound: An Agentic Multimodal Model Activating Evidence-seeking Pathological Diagnosis

2025-12-29 · Shengyi Hua, Jianfeng Wu, Tianle Shen, Kangzhe Hu 외 arxiv

Recent pathological foundation models have substantially advanced visual representation learning and multimodal interaction. However, most models still rely on a static inference paradigm in which whole-slide images are …

Representation LearningReinforcement Learning

Active Evidence-Seeking and Diagnostic Reasoning in Large Language Models for Clinical Decision Support

2026-05-21 · Chen Zhan, Xihe Qiu, Xiaoyu Tan, Xibing Zhuang 외 arxiv

Large language models perform well on static medical examinations, yet clinical diagnosis often requires iterative evidence gathering under uncertainty. Building on prior interactive evaluation efforts, we introduce an O…

PathAgentBench: Benchmarking Evidence-Seeking Vision-Language Models on Whole-Slide Pathology Image

2026-07-21 · Dankai Liao, Tianyi Zhang, Yufeng Wu, Xinyue Zhang 외 arxiv

Whole-slide image (WSI) diagnosis requires identifying diagnostically relevant regions, examining them across magnifications, and integrating multi-scale evidence. However, most existing pathology benchmarks evaluate mod…

Image Retrieval

Video-o3: Native Interleaved Clue Seeking for Long Video Multi-Hop Reasoning

2026-01-30 · Xiangyu Zeng, Zhiqiu Zhang, Yuhan Zhu, Xinhao Li 외 arxiv

Existing multimodal large language models for long-video understanding predominantly rely on uniform sampling and single-turn inference, limiting their ability to identify sparse yet critical evidence amid extensive redu…

Reinforcement Learning

CXReasonAgent: Evidence-Grounded Diagnostic Reasoning Agent for Chest X-rays

2026-02-26 · Hyungyung Lee, Hangyul Yoon, Edward Choi arxiv

Chest X-ray plays a central role in thoracic diagnosis, and its interpretation inherently requires multi-step, evidence-grounded reasoning. However, large vision-language models (LVLMs) often generate plausible responses…