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Reinforcement Learning Framework for Deep Brain Stimulation Study

2020-02-22 · Dmitrii Krylov, Remi Tachet, Romain Laroche, Michael Rosenblum, Dmitry V. Dylov

Malfunctioning neurons in the brain sometimes operate synchronously, reportedly causing many neurological diseases, e.g. Parkinson's. Suppression and control of this collective synchronous activity are therefore of great importance for neuroscience, and can only rely on limited engineering trials due to the need to experiment with live human brains. We present the first Reinforcement Learning gym framework that emulates this collective behavior of neurons and allows us to find suppression parameters for the environment of synthetic degenerate models of neurons. We successfully suppress synchrony via RL for three pathological signaling regimes, characterize the framework's stability to noise, and further remove the unwanted oscillations by engaging multiple PPO agents.

📄 PDF Abstract BibTeX arXiv:2002.10948

Code (1)

cviaai/RL-DBS 공식 구현

Tasks

reinforcement-learningReinforcement LearningReinforcement Learning (RL)

Methods 이 논문이 사용한 방법론

Entropy Regularization 설명 없음
PPO Proximal Policy Optimization, or PPO, is a policy gradient method for reinforcement learning. The motivation was to have an algorithm with the data efficiency and reliable…

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