SingleStrip: learning skull-stripping from a single labeled example
Deep learning segmentation relies heavily on labeled data, but manual labeling is laborious and time-consuming, especially for volumetric images such as brain magnetic resonance imaging (MRI). While recent domain-randomization techniques alleviate the dependency on labeled data by synthesizing diverse training images from label maps, they offer limited anatomical variability when very few label maps are available. Semi-supervised self-training addresses label scarcity by iteratively incorporating model predictions into the training set, enabling networks to learn from unlabeled data. In this work, we combine domain randomization with self-training to train three-dimensional skull-stripping networks using as little as a single labeled example. First, we automatically bin voxel intensities, yielding labels we use to synthesize images for training an initial skull-stripping model. Second, we train a convolutional autoencoder (AE) on the labeled example and use its reconstruction error to assess the quality of brain masks predicted for unlabeled data. Third, we select the top-ranking pseudo-labels to fine-tune the network, achieving skull-stripping performance on out-of-distribution data that approaches models trained with more labeled images. We compare AE-based ranking to consistency-based ranking under test-time augmentation, finding that the AE approach yields a stronger correlation with segmentation accuracy. Our results highlight the potential of combining domain randomization and AE-based quality control to enable effective semi-supervised segmentation from extremely limited labeled data. This strategy may ease the labeling burden that slows progress in studies involving new anatomical structures or emerging imaging techniques.
Code (0)
등록된 구현이 없습니다.
Similar Papers 제목 키워드 기반
Fast Infant MRI Skullstripping with Multiview 2D Convolutional Neural Networks
Skullstripping is defined as the task of segmenting brain tissue from a full head magnetic resonance image~(MRI). It is a critical component in neuroimage processing pipelines. Downstream deformable registration and whol…
Brain SegmentationSynthStrip: Skull-Stripping for Any Brain Image
The removal of non-brain signal from magnetic resonance imaging (MRI) data, known as skull-stripping, is an integral component of many neuroimage analysis streams. Despite their abundance, popular classical skull-strippi…
Skull StrippingBoosting Skull-Stripping Performance for Pediatric Brain Images
Skull-stripping is the removal of background and non-brain anatomical features from brain images. While many skull-stripping tools exist, few target pediatric populations. With the emergence of multi-institutional pediat…
Skull StrippingPerformance Evaluation of Vanilla, Residual, and Dense 2D U-Net Architectures for Skull Stripping of Augmented 3D T1-weighted MRI Head Scans
Skull Stripping is a requisite preliminary step in most diagnostic neuroimaging applications. Manual Skull Stripping methods define the gold standard for the domain but are time-consuming and challenging to integrate int…
DiagnosticMRI segmentationSkull StrippingAttention-based convolutional neural network for perfusion T2-weighted MR images preprocessing
Accurate skull-stripping is crucial preprocessing in dynamic susceptibility contrast-enhanced perfusion magnetic resonance data analysis. The presence of non-brain tissues impacts the perfusion parameters assessment. In …
AnatomySkull Stripping