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Structure Causal Models and LLMs Integration in Medical Visual Question Answering

2025-05-05 · Zibo Xu, Qiang Li, Weizhi Nie, Weijie Wang, AnAn Liu

Medical Visual Question Answering (MedVQA) aims to answer medical questions according to medical images. However, the complexity of medical data leads to confounders that are difficult to observe, so bias between images and questions is inevitable. Such cross-modal bias makes it challenging to infer medically meaningful answers. In this work, we propose a causal inference framework for the MedVQA task, which effectively eliminates the relative confounding effect between the image and the question to ensure the precision of the question-answering (QA) session. We are the first to introduce a novel causal graph structure that represents the interaction between visual and textual elements, explicitly capturing how different questions influence visual features. During optimization, we apply the mutual information to discover spurious correlations and propose a multi-variable resampling front-door adjustment method to eliminate the relative confounding effect, which aims to align features based on their true causal relevance to the question-answering task. In addition, we also introduce a prompt strategy that combines multiple prompt forms to improve the model's ability to understand complex medical data and answer accurately. Extensive experiments on three MedVQA datasets demonstrate that 1) our method significantly improves the accuracy of MedVQA, and 2) our method achieves true causal correlations in the face of complex medical data.

📄 PDF Abstract BibTeX arXiv:2505.02703

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Causal InferenceMedical Visual Question AnsweringQuestion AnsweringVisual Question Answering

Methods 이 논문이 사용한 방법론

Causal inference Causal inference is the process of drawing a conclusion about a causal connection based on the conditions of the occurrence of an effect. The main difference between causal…
ALIGN In the ALIGN method, visual and language representations are jointly trained from noisy image alt-text data. The image and text encoders are learned via contrastive loss…

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