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Sub-Scalp Brain-Computer Interface Device Design and Fabrication

2025-04-17 · Timothy B. Mahoney, David B. Grayden, Sam E. John

Current brain-computer interfaces (BCI) face limitations in signal acquisition. While sub-scalp EEG offers a potential solution, existing devices prioritize chronic seizure monitoring and lack features suited for BCI applications. This work addresses this gap by outlining key specifications for sub-scalp BCI devices, focusing on channel count, sampling rate, power efficiency, and form factor. We present the Set-And-Forget EEG (SAFE) system, a custom-built amplifier and wireless transmitter meeting these criteria. This compact (12x12 mm), six-channel device offers 1024 Hz sampling and Bluetooth Low Energy data transmission. Validation using generated sinusoids and electrocorticography recordings of visual evoked potentials in sheep models demonstrated low noise recording. Future animal studies will assess sub-scalp EEG signal quality for BCI applications. This data lays the groundwork for human trials, ultimately paving the way for chronic, in-home BCIs that empower individuals with physical disabilities.

📄 PDF Abstract BibTeX arXiv:2504.12578

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