Towards Predicting Temporal Changes in a Patient's Chest X-ray Images based on Electronic Health Records
Chest X-ray (CXR) is an important diagnostic tool widely used in hospitals to assess patient conditions and monitor changes over time. Recently, generative models, specifically diffusion-based models, have shown promise in generating realistic synthetic CXRs. However, these models mainly focus on conditional generation using single-time-point data, i.e., generating CXRs conditioned on their corresponding reports from a specific time. This limits their clinical utility, particularly for capturing temporal changes. To address this limitation, we propose a novel framework, EHRXDiff, which predicts future CXR images by integrating previous CXRs with subsequent medical events, e.g., prescriptions, lab measures, etc. Our framework dynamically tracks and predicts disease progression based on a latent diffusion model, conditioned on the previous CXR image and a history of medical events. We comprehensively evaluate the performance of our framework across three key aspects, including clinical consistency, demographic consistency, and visual realism. Results show that our framework generates high-quality, realistic future images that effectively capture potential temporal changes. This suggests that our framework could be further developed to support clinical decision-making and provide valuable insights for patient monitoring and treatment planning in the medical field. The code is available at https://github.com/dek924/EHRXDiff.
Code (1)
Tasks
DiagnosticMethods 이 논문이 사용한 방법론
Similar Papers 제목 키워드 기반
Improving Chest X-Ray Classification by RNN-based Patient Monitoring
Chest X-Ray imaging is one of the most common radiological tools for detection of various pathologies related to the chest area and lung function. In a clinical setting, automated assessment of chest radiographs has the …
Decision Makingimage-classificationImage ClassificationX-ray ClassificationWisdomNet: Prognosis of COVID-19 with Slender Prospect of False Negative Cases and Vaticinating the Probability of Maturation to ARDS using Posteroanterior Chest X-Rays
Coronavirus is a large virus family consisting of diverse viruses, some of which disseminate among mammals and others cause sickness among humans. COVID-19 is highly contagious and is rapidly spreading, rendering its ear…
PrognosisSimplified Transfer Learning for Chest Radiography Models Using Less Data
Developing deep learning models for radiology requires large data sets and substantial computational resources. Data set size limitations can be further exacerbated by distribution shifts, such as rapid changes in patien…
Contrastive LearningTransfer LearningDeep Learning on Chest X-ray Images to Detect and Evaluate Pneumonia Cases at the Era of COVID-19
Coronavirus disease 2019 (COVID-19) is an infectious disease with first symptoms similar to the flu. COVID-19 appeared first in China and very quickly spreads to the rest of the world, causing then the 2019-20 coronaviru…
Deep LearningAssessing the Performance of Automated Prediction and Ranking of Patient Age from Chest X-rays Against Clinicians
Understanding the internal physiological changes accompanying the aging process is an important aspect of medical image interpretation, with the expected changes acting as a baseline when reporting abnormal findings. Dee…
Age EstimationGenerative Adversarial NetworkPrediction