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Zero-shot CT Field-of-view Completion with Unconditional Generative Diffusion Prior

2023-04-07 · Kaiwen Xu, Aravind R. Krishnan, Thomas Z. Li, Yuankai Huo, Kim L. Sandler, Fabien Maldonado, Bennett A. Landman

Anatomically consistent field-of-view (FOV) completion to recover truncated body sections has important applications in quantitative analyses of computed tomography (CT) with limited FOV. Existing solution based on conditional generative models relies on the fidelity of synthetic truncation patterns at training phase, which poses limitations for the generalizability of the method to potential unknown types of truncation. In this study, we evaluate a zero-shot method based on a pretrained unconditional generative diffusion prior, where truncation pattern with arbitrary forms can be specified at inference phase. In evaluation on simulated chest CT slices with synthetic FOV truncation, the method is capable of recovering anatomically consistent body sections and subcutaneous adipose tissue measurement error caused by FOV truncation. However, the correction accuracy is inferior to the conditionally trained counterpart.

📄 PDF Abstract BibTeX arXiv:2304.03760

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Computed Tomography (CT)

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Diffusion Diffusion models generate samples by gradually removing noise from a signal, and their training objective can be expressed as a reweighted variational lower-bound…

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