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Papers Molecular Graph Generation

“Molecular Graph Generation” 태그가 달린 논문 54편 · 필터 해제

Pretraining Generative Flow Networks with Inexpensive Rewards for Molecular Graph Generation

2025-03-08 · Mohit Pandey, Gopeshh Subbaraj, Artem Cherkasov, Martin Ester 외

Generative Flow Networks (GFlowNets) have recently emerged as a suitable framework for generating diverse and high-quality molecular structures by learning from rewards treated as unnormalized distributions. Previous wor…

Drug DesignGraph GenerationMolecular Graph GenerationUnsupervised Pre-training

Learning-Order Autoregressive Models with Application to Molecular Graph Generation

2025-03-07 · Zhe Wang, Jiaxin Shi, Nicolas Heess, Arthur Gretton 외

Autoregressive models (ARMs) have become the workhorse for sequence generation tasks, since many problems can be modeled as next-token prediction. While there appears to be a natural ordering for text (i.e., left-to-righ…

Graph GenerationMolecular Graph Generation

FragFM: Hierarchical Framework for Efficient Molecule Generation via Fragment-Level Discrete Flow Matching

2025-02-19 · Joongwon Lee, SeongHwan Kim, Seokhyun Moon, Hyunwoo Kim 외

We introduce FragFM, a novel hierarchical framework via fragment-level discrete flow matching for efficient molecular graph generation. FragFM generates molecules at the fragment level, leveraging a coarse-to-fine autoen…

DiversityDrug DiscoveryEfficient ExplorationGraph Generation+1

Flatten Graphs as Sequences: Transformers are Scalable Graph Generators

2025-02-04 · Dexiong Chen, Markus Krimmel, Karsten Borgwardt

We introduce AutoGraph, a novel autoregressive framework for generating large attributed graphs using decoder-only transformers. At the core of our approach is a reversible "flattening" process that transforms graphs int…

DecoderGraph GenerationLanguage ModelingLanguage Modelling+1

Improving Molecular Graph Generation with Flow Matching and Optimal Transport

2024-11-08 · Xiaoyang Hou, Tian Zhu, Milong Ren, Dongbo Bu 외

Generating molecular graphs is crucial in drug design and discovery but remains challenging due to the complex interdependencies between nodes and edges. While diffusion models have demonstrated their potentiality in mol…

Drug DesignGraph GenerationMolecular Graph Generation

GUISE: Graph GaUssIan Shading watErmark

2024-10-14 · Renyi Yang

In the expanding field of generative artificial intelligence, integrating robust watermarking technologies is essential to protect intellectual property and maintain content authenticity. Traditionally, watermarking tech…

Graph GenerationMolecular Graph Generation

Training-Free Guidance for Discrete Diffusion Models for Molecular Generation

2024-09-11 · Thomas J. Kerby, Kevin R. Moon

Training-free guidance methods for continuous data have seen an explosion of interest due to the fact that they enable foundation diffusion models to be paired with interchangable guidance models. Currently, equivalent g…

Graph GenerationMolecular Graph Generation

Instruction-Based Molecular Graph Generation with Unified Text-Graph Diffusion Model

2024-08-19 · Yuran Xiang, Haiteng Zhao, Chang Ma, Zhi-Hong Deng

Recent advancements in computational chemistry have increasingly focused on synthesizing molecules based on textual instructions. Integrating graph generation with these instructions is complex, leading most current meth…

Computational chemistryDenoisingGraph GenerationMolecular Graph Generation

GraphSPNs: Sum-Product Networks Benefit From Canonical Orderings

2024-08-18 · Milan Papež, Martin Rektoris, Václav Šmídl, Tomáš Pevný

Deep generative models have recently made a remarkable progress in capturing complex probability distributions over graphs. However, they are intractable and thus unable to answer even the most basic probabilistic infere…

Molecular Graph Generationvalid

Lift Your Molecules: Molecular Graph Generation in Latent Euclidean Space

2024-06-15 · Mohamed Amine Ketata, Nicholas Gao, Johanna Sommer, Tom Wollschläger 외

We introduce a new framework for molecular graph generation with 3D molecular generative models. Our Synthetic Coordinate Embedding (SyCo) framework maps molecular graphs to Euclidean point clouds via synthetic conformer…

Edge ClassificationGraph GenerationGraph Neural NetworkMolecular Graph Generation+1

3M-Diffusion: Latent Multi-Modal Diffusion for Language-Guided Molecular Structure Generation

2024-03-11 · Huaisheng Zhu, Teng Xiao, Vasant G Honavar

Generating molecular structures with desired properties is a critical task with broad applications in drug discovery and materials design. We propose 3M-Diffusion, a novel multi-modal molecular graph generation method, t…

DecoderDrug DiscoveryGraph GenerationMolecular Graph Generation+1

Overcoming Order in Autoregressive Graph Generation

2024-02-04 · Edo Cohen-Karlik, Eyal Rozenberg, Daniel Freedman

Graph generation is a fundamental problem in various domains, including chemistry and social networks. Recent work has shown that molecular graph generation using recurrent neural networks (RNNs) is advantageous compared…

Graph GenerationMolecular Graph Generationvalid

A Simple and Scalable Representation for Graph Generation

2023-12-04 · Yunhui Jang, Seul Lee, Sungsoo Ahn

Recently, there has been a surge of interest in employing neural networks for graph generation, a fundamental statistical learning problem with critical applications like molecule design and community analysis. However, …

Graph GenerationMolecular Graph Generation

Will More Expressive Graph Neural Networks do Better on Generative Tasks?

2023-08-23 · Xiandong Zou, Xiangyu Zhao, Pietro Liò, Yiren Zhao

Graph generation poses a significant challenge as it involves predicting a complete graph with multiple nodes and edges based on simply a given label. This task also carries fundamental importance to numerous real-world …

Bayesian OptimisationGraph GenerationGraph Neural NetworkMolecular Graph Generation

Learning Joint 2D & 3D Diffusion Models for Complete Molecule Generation

2023-05-21 · Han Huang, Leilei Sun, Bowen Du, Weifeng Lv

Designing new molecules is essential for drug discovery and material science. Recently, deep generative models that aim to model molecule distribution have made promising progress in narrowing down the chemical research …

3D Molecule GenerationDrug DiscoveryGraph GenerationMolecular Graph Generation

MolHF: A Hierarchical Normalizing Flow for Molecular Graph Generation

2023-05-15 · Yiheng Zhu, Zhenqiu Ouyang, Ben Liao, Jialu Wu 외

Molecular de novo design is a critical yet challenging task in scientific fields, aiming to design novel molecular structures with desired property profiles. Significant progress has been made by resorting to generative …

Graph GenerationMolecular Graph GenerationRepresentation Learning

Target Specific De Novo Design of Drug Candidate Molecules with Graph Transformer-based Generative Adversarial Networks

2023-02-15 · Atabey Ünlü, Elif Çevrim, Melih Gökay Yiğit, Ahmet Sarıgün 외

Discovering novel drug candidate molecules is one of the most fundamental and critical steps in drug development. Generative deep learning models, which create synthetic data given a probability distribution, offer a hig…

Generative Adversarial NetworkMolecular Graph Generation

Geometry-Complete Diffusion for 3D Molecule Generation and Optimization

2023-02-08 · Alex Morehead, Jianlin Cheng

Denoising diffusion probabilistic models (DDPMs) have pioneered new state-of-the-art results in disciplines such as computer vision and computational biology for diverse tasks ranging from text-guided image generation to…

3D Molecule GenerationDenoisingGraph GenerationImage Generation+5

Graph Generation with Diffusion Mixture

2023-02-07 · Jaehyeong Jo, DongKi Kim, Sung Ju Hwang

Generation of graphs is a major challenge for real-world tasks that require understanding the complex nature of their non-Euclidean structures. Although diffusion models have achieved notable success in graph generation …

3D Molecule GenerationGraph GenerationInductive BiasMolecular Graph Generation

Conditional Diffusion Based on Discrete Graph Structures for Molecular Graph Generation

2023-01-01 · Han Huang, Leilei Sun, Bowen Du, Weifeng Lv

Learning the underlying distribution of molecular graphs and generating high-fidelity samples is a fundamental research problem in drug discovery and material science. However, accurately modeling distribution and rapidl…

Drug DiscoveryGraph GenerationGraph SamplingMolecular Graph Generation
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