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Knowledge-Guided Prompt Learning for Lifespan Brain MR Image Segmentation

2024-07-31 · Lin Teng, Zihao Zhao, Jiawei Huang, Zehong Cao, Runqi Meng, Feng Shi, Dinggang Shen

Automatic and accurate segmentation of brain MR images throughout the human lifespan into tissue and structure is crucial for understanding brain development and diagnosing diseases. However, challenges arise from the intricate variations in brain appearance due to rapid early brain development, aging, and disorders, compounded by the limited availability of manually-labeled datasets. In response, we present a two-step segmentation framework employing Knowledge-Guided Prompt Learning (KGPL) for brain MRI. Specifically, we first pre-train segmentation models on large-scale datasets with sub-optimal labels, followed by the incorporation of knowledge-driven embeddings learned from image-text alignment into the models. The introduction of knowledge-wise prompts captures semantic relationships between anatomical variability and biological processes, enabling models to learn structural feature embeddings across diverse age groups. Experimental findings demonstrate the superiority and robustness of our proposed method, particularly noticeable when employing Swin UNETR as the backbone. Our approach achieves average DSC values of 95.17% and 94.19% for brain tissue and structure segmentation, respectively. Our code is available at https://github.com/TL9792/KGPL.

📄 PDF Abstract BibTeX arXiv:2407.21328

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Image SegmentationPrompt LearningSegmentationSemantic Segmentation

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Max Pooling Max Pooling is a pooling operation that calculates the maximum value for patches of a feature map, and uses it to create a downsampled (pooled) feature map. It is usually…
Softmax The Softmax output function transforms a previous layer's output into a vector of probabilities. It is commonly used for multiclass classification. Given an input vector $x$…
Dense Connections Dense Connections, or Fully Connected Connections, are a type of layer in a deep neural network that use a linear operation where every input is connected to every output…
Batch Normalization 설명 없음
Linear Layer A Linear Layer is a projection $\mathbf{XW + b}$.
Concatenated Skip Connection A Concatenated Skip Connection is a type of skip connection that seeks to reuse features by concatenating them to new layers, allowing more information to be retained from…
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