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DCSNet: A Lightweight Knowledge Distillation-Based Model with Explainable AI for Lung Cancer Diagnosis from Histopathological Images

2025-05-14 · Sadman Sakib Alif, Nasim Anzum Promise, Fiaz Al Abid, Aniqua Nusrat Zereen

Lung cancer is a leading cause of cancer-related deaths globally, where early detection and accurate diagnosis are critical for improving survival rates. While deep learning, particularly convolutional neural networks (CNNs), has revolutionized medical image analysis by detecting subtle patterns indicative of early-stage lung cancer, its adoption faces challenges. These models are often computationally expensive and require significant resources, making them unsuitable for resource constrained environments. Additionally, their lack of transparency hinders trust and broader adoption in sensitive fields like healthcare. Knowledge distillation addresses these challenges by transferring knowledge from large, complex models (teachers) to smaller, lightweight models (students). We propose a knowledge distillation-based approach for lung cancer detection, incorporating explainable AI (XAI) techniques to enhance model transparency. Eight CNNs, including ResNet50, EfficientNetB0, EfficientNetB3, and VGG16, are evaluated as teacher models. We developed and trained a lightweight student model, Distilled Custom Student Network (DCSNet) using ResNet50 as the teacher. This approach not only ensures high diagnostic performance in resource-constrained settings but also addresses transparency concerns, facilitating the adoption of AI-driven diagnostic tools in healthcare.

📄 PDF Abstract BibTeX arXiv:2505.09334

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DiagnosticKnowledge DistillationLung Cancer DiagnosisMedical Image Analysis

Methods 이 논문이 사용한 방법론

Knowledge Distillation A very simple way to improve the performance of almost any machine learning algorithm is to train many different models on the same data and then to average their predictions.…

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