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First steps on Gamification of Lung Fluid Cells Annotations in the Flower Domain

2021-11-05 · Sonja Kunzmann, Christian Marzahl, Felix Denzinger, Christof A. Bertram, Robert Klopfleisch, Katharina Breininger, Vincent Christlein, Andreas Maier

Annotating data, especially in the medical domain, requires expert knowledge and a lot of effort. This limits the amount and/or usefulness of available medical data sets for experimentation. Therefore, developing strategies to increase the number of annotations while lowering the needed domain knowledge is of interest. A possible strategy is the use of gamification, i.e. transforming the annotation task into a game. We propose an approach to gamify the task of annotating lung fluid cells from pathological whole slide images (WSIs). As the domain is unknown to non-expert annotators, we transform images of cells to the domain of flower images using a CycleGAN architecture. In this more assessable domain, non-expert annotators can be (t)asked to annotate different kinds of flowers in a playful setting. In order to provide a proof of concept, this work shows that the domain transfer is possible by evaluating an image classification network trained on real cell images and tested on the cell images generated by the CycleGAN network (reconstructed cell images) as well as real cell images. The classification network reaches an average accuracy of 94.73 % on the original lung fluid cells and 95.25 % on the transformed lung fluid cells, respectively. Our study lays the foundation for future research on gamification using CycleGANs.

📄 PDF Abstract BibTeX arXiv:2111.03663

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Tasks

image-classificationImage Classificationwhole slide images

Methods 이 논문이 사용한 방법론

FPN 설명 없음
1x1 Convolution A 1 x 1 Convolution is a convolution with some special properties in that it can be used for dimensionality reduction,…
Residual Connection 설명 없음
Batch Normalization 설명 없음
Convolution A convolution is a type of matrix operation, consisting of a kernel, a small matrix of weights, that slides over input data performing element-wise multiplication with the…
Focal Loss A Focal Loss function addresses class imbalance during training in tasks like object detection. Focal loss applies a modulating term to the cross entropy loss in order to…
Tanh Activation 설명 없음
Instance Normalization Instance Normalization (also known as contrast normalization) is a normalization layer where: $$ y_{tijk} = \frac{x_{tijk} - \mu_{ti}}{\sqrt{\sigma_{ti}^2 +…

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whole slide images