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Multi-head Attention-based Deep Multiple Instance Learning

2024-04-08 · Hassan Keshvarikhojasteh, Josien Pluim, Mitko Veta

This paper introduces MAD-MIL, a Multi-head Attention-based Deep Multiple Instance Learning model, designed for weakly supervised Whole Slide Images (WSIs) classification in digital pathology. Inspired by the multi-head attention mechanism of the Transformer, MAD-MIL simplifies model complexity while achieving competitive results against advanced models like CLAM and DS-MIL. Evaluated on the MNIST-BAGS and public datasets, including TUPAC16, TCGA BRCA, TCGA LUNG, and TCGA KIDNEY, MAD-MIL consistently outperforms ABMIL. This demonstrates enhanced information diversity, interpretability, and efficiency in slide representation. The model's effectiveness, coupled with fewer trainable parameters and lower computational complexity makes it a promising solution for automated pathology workflows. Our code is available at https://github.com/tueimage/MAD-MIL.

📄 PDF Abstract BibTeX arXiv:2404.05362

Code (1)

tueimage/mad-mil 공식 구현 pytorch

Tasks

DiversityMultiple Instance Learningwhole slide images

Methods 이 논문이 사용한 방법론

Attention 설명 없음
Softmax The Softmax output function transforms a previous layer's output into a vector of probabilities. It is commonly used for multiclass classification. Given an input vector $x$…
Linear Layer A Linear Layer is a projection $\mathbf{XW + b}$.
Layer Normalization Unlike batch normalization, Layer Normalization directly estimates the normalization statistics from the summed inputs…
Dense Connections Dense Connections, or Fully Connected Connections, are a type of layer in a deep neural network that use a linear operation where every input is connected to every output…
Label Smoothing Label Smoothing is a regularization technique that introduces noise for the labels. This accounts for the fact that datasets may have mistakes in them, so maximizing the…
Residual Connection 설명 없음
Dropout Dropout is a regularization technique for neural networks that drops a unit (along with connections) at training time with a specified probability $p$ (a common value is…

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