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Advancing 3D Medical Image Segmentation: Unleashing the Potential of Planarian Neural Networks in Artificial Intelligence

2025-05-07 · Ziyuan Huang, Kevin Huggins, Srikar Bellur

Our study presents PNN-UNet as a method for constructing deep neural networks that replicate the planarian neural network (PNN) structure in the context of 3D medical image data. Planarians typically have a cerebral structure comprising two neural cords, where the cerebrum acts as a coordinator, and the neural cords serve slightly different purposes within the organism's neurological system. Accordingly, PNN-UNet comprises a Deep-UNet and a Wide-UNet as the nerve cords, with a densely connected autoencoder performing the role of the brain. This distinct architecture offers advantages over both monolithic (UNet) and modular networks (Ensemble-UNet). Our outcomes on a 3D MRI hippocampus dataset, with and without data augmentation, demonstrate that PNN-UNet outperforms the baseline UNet and several other UNet variants in image segmentation.

📄 PDF Abstract BibTeX arXiv:2505.04664

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Data AugmentationHippocampusImage SegmentationMedical Image SegmentationSemantic Segmentation

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