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Can a single image processing algorithm work equally well across all phases of DCE-MRI?

2023-06-22 · Adam G. Tattersall, Keith A. Goatman, Lucy E. Kershaw, Scott I. K. Semple, Sonia Dahdouh

Image segmentation and registration are said to be challenging when applied to dynamic contrast enhanced MRI sequences (DCE-MRI). The contrast agent causes rapid changes in intensity in the region of interest and elsewhere, which can lead to false positive predictions for segmentation tasks and confound the image registration similarity metric. While it is widely assumed that contrast changes increase the difficulty of these tasks, to our knowledge no work has quantified these effects. In this paper we examine the effect of training with different ratios of contrast enhanced (CE) data on two popular tasks: segmentation with nnU-Net and Mask R-CNN and registration using VoxelMorph and VTN. We experimented further by strategically using the available datasets through pretraining and fine tuning with different splits of data. We found that to create a generalisable model, pretraining with CE data and fine tuning with non-CE data gave the best result. This interesting find could be expanded to other deep learning based image processing tasks with DCE-MRI and provide significant improvements to the models performance.

📄 PDF Abstract BibTeX arXiv:2306.12988

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Tasks

AllImage RegistrationImage SegmentationSegmentationSemantic Segmentation

Methods 이 논문이 사용한 방법론

Convolution A convolution is a type of matrix operation, consisting of a kernel, a small matrix of weights, that slides over input data performing element-wise multiplication with the…
RPN A Region Proposal Network, or RPN, is a fully convolutional network that simultaneously predicts object bounds and objectness scores at each position. The RPN is trained…
RoIAlign Region of Interest Align, or RoIAlign, is an operation for extracting a small feature map from each RoI in detection and segmentation based tasks. It removes the harsh…
Softmax The Softmax output function transforms a previous layer's output into a vector of probabilities. It is commonly used for multiclass classification. Given an input vector $x$…
Mask R-CNN Mask R-CNN extends Faster R-CNN to solve instance segmentation tasks. It achieves this by adding a branch for predicting an…

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