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CTI-Unet: Cascaded Threshold Integration for Improved U-Net Segmentation of Pathology Images

2025-04-08 · Mingyang Zhu, Yuqiu Liang, Jiacheng Wang

Chronic kidney disease (CKD) is a growing global health concern, necessitating precise and efficient image analysis to aid diagnosis and treatment planning. Automated segmentation of kidney pathology images plays a central role in facilitating clinical workflows, yet conventional segmentation models often require delicate threshold tuning. This paper proposes a novel \textit{Cascaded Threshold-Integrated U-Net (CTI-Unet)} to overcome the limitations of single-threshold segmentation. By sequentially integrating multiple thresholded outputs, our approach can reconcile noise suppression with the preservation of finer structural details. Experiments on the challenging KPIs2024 dataset demonstrate that CTI-Unet outperforms state-of-the-art architectures such as nnU-Net, Swin-Unet, and CE-Net, offering a robust and flexible framework for kidney pathology image segmentation.

📄 PDF Abstract BibTeX arXiv:2504.05640

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Image SegmentationSegmentationSemantic Segmentation

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Concatenated Skip Connection A Concatenated Skip Connection is a type of skip connection that seeks to reuse features by concatenating them to new layers, allowing more information to be retained from…
Convolution A convolution is a type of matrix operation, consisting of a kernel, a small matrix of weights, that slides over input data performing element-wise multiplication with the…
Max Pooling Max Pooling is a pooling operation that calculates the maximum value for patches of a feature map, and uses it to create a downsampled (pooled) feature map. It is usually…
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