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Diff-CL: A Novel Cross Pseudo-Supervision Method for Semi-supervised Medical Image Segmentation

2025-03-12 · Xiuzhen Guo, Lianyuan Yu, Ji Shi, Na lei, Hongxiao Wang

Semi-supervised learning utilizes insights from unlabeled data to improve model generalization, thereby reducing reliance on large labeled datasets. Most existing studies focus on limited samples and fail to capture the overall data distribution. We contend that combining distributional information with detailed information is crucial for achieving more robust and accurate segmentation results. On the one hand, with its robust generative capabilities, diffusion models (DM) learn data distribution effectively. However, it struggles with fine detail capture, leading to generated images with misleading details. Combining DM with convolutional neural networks (CNNs) enables the former to learn data distribution while the latter corrects fine details. While capturing complete high-frequency details by CNNs requires substantial computational resources and is susceptible to local noise. On the other hand, given that both labeled and unlabeled data come from the same distribution, we believe that regions in unlabeled data similar to overall class semantics to labeled data are likely to belong to the same class, while regions with minimal similarity are less likely to. This work introduces a semi-supervised medical image segmentation framework from the distribution perspective (Diff-CL). Firstly, we propose a cross-pseudo-supervision learning mechanism between diffusion and convolution segmentation networks. Secondly, we design a high-frequency mamba module to capture boundary and detail information globally. Finally, we apply contrastive learning for label propagation from labeled to unlabeled data. Our method achieves state-of-the-art (SOTA) performance across three datasets, including left atrium, brain tumor, and NIH pancreas datasets.

📄 PDF Abstract BibTeX arXiv:2503.09408

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Tasks

Contrastive LearningImage SegmentationMambaMedical Image SegmentationSemantic SegmentationSemi-supervised Medical Image Segmentation

Methods 이 논문이 사용한 방법론

Mamba Foundation models, now powering most of the exciting applications in deep learning, are almost universally based on the Transformer architecture and its core attention module.…
Diffusion Diffusion models generate samples by gradually removing noise from a signal, and their training objective can be expressed as a reweighted variational lower-bound…
Contrastive Learning 설명 없음
Focus 설명 없음
Convolution A convolution is a type of matrix operation, consisting of a kernel, a small matrix of weights, that slides over input data performing element-wise multiplication with the…

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