Neural Pre-Processing: A Learning Framework for End-to-end Brain MRI Pre-processing
Head MRI pre-processing involves converting raw images to an intensity-normalized, skull-stripped brain in a standard coordinate space. In this paper, we propose an end-to-end weakly supervised learning approach, called Neural Pre-processing (NPP), for solving all three sub-tasks simultaneously via a neural network, trained on a large dataset without individual sub-task supervision. Because the overall objective is highly under-constrained, we explicitly disentangle geometric-preserving intensity mapping (skull-stripping and intensity normalization) and spatial transformation (spatial normalization). Quantitative results show that our model outperforms state-of-the-art methods which tackle only a single sub-task. Our ablation experiments demonstrate the importance of the architecture design we chose for NPP. Furthermore, NPP affords the user the flexibility to control each of these tasks at inference time. The code and model are freely-available at \url{https://github.com/Novestars/Neural-Pre-processing}.
Code (1)
Tasks
ReconstructionSkull StrippingWeakly-supervised LearningSimilar Papers 제목 키워드 기반
Towards a Governance Framework for Brain Data
The increasing availability of brain data within and outside the biomedical field, combined with the application of artificial intelligence (AI) to brain data analysis, poses a challenge for ethics and governance. We ide…
EthicsAn Optimization Framework for Processing and Transfer Learning for the Brain Tumor Segmentation
Tumor segmentation from multi-modal brain MRI images is a challenging task due to the limited samples, high variance in shapes and uneven distribution of tumor morphology. The performance of automated medical image segme…
Brain Tumor SegmentationImage SegmentationMedical Image SegmentationSegmentation+3Do Large Language Models Mirror Cognitive Language Processing?
Large Language Models (LLMs) have demonstrated remarkable abilities in text comprehension and logical reasoning, indicating that the text representations learned by LLMs can facilitate their language processing capabilit…
ChatbotLogical ReasoningMMLUReading ComprehensionBrain-tuned Speech Models Better Reflect Speech Processing Stages in the Brain
Pretrained self-supervised speech models excel in speech tasks but do not reflect the hierarchy of human speech processing, as they encode rich semantics in middle layers and poor semantics in late layers. Recent work sh…
Centralized and distributed cognitive task processing in the human connectome
A key question in modern neuroscience is how cognitive changes in a human brain can be quantified and captured by functional connectomes (FC) . A systematic approach to measure pairwise functional distance at different b…