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Papers Nuclear Segmentation

“Nuclear Segmentation” 태그가 달린 논문 38편 · 필터 해제

VitaminP: cross-modal learning enables whole-cell segmentation from routine histology

2026-04-26 · Yasin Shokrollahi, Karina B. Pinao Gonzales, Elizve N. Barrientos Toro, Paul Acosta 외 arxiv

Accurate whole-cell and nuclear segmentation is essential for precision pathology and spatial omics, yet routine hematoxylin and eosin (H&E) staining provides limited cytoplasmic contrast, restricting analyses to nuclei.…

Nuclear SegmentationCell Segmentation

Benchmarking Computational Pathology Foundation Models For Semantic Segmentation

2026-02-21 · Lavish Ramchandani, Aashay Tinaikar, Dev Kumar Das, Rohit Garg 외 arxiv

In recent years, foundation models such as CLIP, DINO,and CONCH have demonstrated remarkable domain generalization and unsupervised feature extraction capabilities across diverse imaging tasks. However, systematic and in…

Semantic SegmentationDomain GeneralizationNuclear Segmentation

A Semantically Enhanced Generative Foundation Model Improves Pathological Image Synthesis

2025-12-15 · Xianchao Guan, Zhiyuan Fan, Yifeng Wang, Fuqiang Chen 외 arxiv

The development of clinical-grade artificial intelligence in pathology is limited by the scarcity of diverse, high-quality annotated datasets. Generative models offer a potential solution but suffer from semantic instabi…

Visual Question AnsweringSelf-Supervised LearningCross-Modal RetrievalNuclear Segmentation

Synthetic-to-Real Transfer Learning for Chromatin-Sensitive PWS Microscopy

2025-10-25 · Jahidul Arafat, Sanjaya Poudel arxiv

Chromatin sensitive partial wave spectroscopic (csPWS) microscopy enables label free detection of nanoscale chromatin packing alterations that occur before visible cellular transformation. However, manual nuclear segment…

Nuclear SegmentationTransfer Learning

MorphGen: Morphology-Guided Representation Learning for Robust Single-Domain Generalization in Histopathological Cancer Classification

2025-08-30 · Hikmat Khan, Syed Farhan Alam Zaidi, Pir Masoom Shah, Kiruthika Balakrishnan 외 arxiv

Domain generalization in computational histopathology is hindered by heterogeneity in whole slide images (WSIs), caused by variations in tissue preparation, staining, and imaging conditions across institutions. Unlike ma…

Representation LearningDomain GeneralizationCancer ClassificationNuclear Segmentation

Unpaired Image-to-Image Translation for Segmentation and Signal Unmixing

2025-05-27 · Nikola Andrejic, Milica Spasic, Igor Mihajlovic, Petra Milosavljevic 외

This work introduces Ui2i, a novel model for unpaired image-to-image translation, trained on content-wise unpaired datasets to enable style transfer across domains while preserving content. Building on CycleGAN, Ui2i inc…

Domain AdaptationImage-to-Image TranslationNuclear SegmentationStyle Transfer+1

APSeg: Auto-Prompt Model with Acquired and Injected Knowledge for Nuclear Instance Segmentation and Classification

2025-04-03 · Liying Xu, Hongliang He, Wei Han, Hanbin Huang 외

Nuclear instance segmentation and classification provide critical quantitative foundations for digital pathology diagnosis. With the advent of the foundational Segment Anything Model (SAM), the accuracy and efficiency of…

ClassificationInstance SegmentationNuclear SegmentationSemantic Segmentation

FrGNet: A fourier-guided weakly-supervised framework for nuclear instance segmentation

2025-02-14 · Peng Ling, Wenxiao Xiong

Nuclear instance segmentation has played a critical role in pathology image analysis. The main challenges arise from the difficulty in accurately segmenting instances and the high cost of precise mask-level annotations f…

Instance SegmentationNuclear SegmentationSemantic Segmentation

Are nuclear masks all you need for improved out-of-domain generalisation? A closer look at cancer classification in histopathology

2024-11-14 · Dhananjay Tomar, Alexander Binder, Andreas Kleppe

Domain generalisation in computational histopathology is challenging because the images are substantially affected by differences among hospitals due to factors like fixation and staining of tissue and imaging equipment.…

AllCancer ClassificationData AugmentationNuclear Segmentation

HoverFast: an accurate, high-throughput, clinically deployable nuclear segmentation tool for brightfield digital pathology images

2024-05-22 · Petros Liakopoulos, Julien Massonnet, Jonatan Bonjour, Medya Tekes Mizrakli 외

In computational digital pathology, accurate nuclear segmentation of Hematoxylin and Eosin (H&E) stained whole slide images (WSIs) is a critical step for many analyses and tissue characterizations. One popular deep learn…

GPUKnowledge DistillationNuclear SegmentationSegmentation+1

Towards Large-Scale Training of Pathology Foundation Models

2024-03-24 · kaiko. ai, Nanne Aben, Edwin D. de Jong, Ioannis Gatopoulos 외

Driven by the recent advances in deep learning methods and, in particular, by the development of modern self-supervised learning algorithms, increased interest and efforts have been devoted to build foundation models (FM…

Nuclear SegmentationSelf-Supervised Learningwhole slide images

CoNIC Challenge: Pushing the Frontiers of Nuclear Detection, Segmentation, Classification and Counting

2023-03-11 · Simon Graham, Quoc Dang Vu, Mostafa Jahanifar, Martin Weigert 외

Nuclear detection, segmentation and morphometric profiling are essential in helping us further understand the relationship between histology and patient outcome. To drive innovation in this area, we setup a community-wid…

Nuclear SegmentationSegmentationSurvival Analysiswhole slide images

Nuclear Segmentation and Classification: On Color & Compression Generalization

2023-01-09 · Quoc Dang Vu, Robert Jewsbury, Simon Graham, Mostafa Jahanifar 외

Since the introduction of digital and computational pathology as a field, one of the major problems in the clinical application of algorithms has been the struggle to generalize well to examples outside the distribution …

ClassificationNuclear SegmentationStyle Transfer

SynCLay: Interactive Synthesis of Histology Images from Bespoke Cellular Layouts

2022-12-28 · Srijay Deshpande, Muhammad Dawood, Fayyaz Minhas, Nasir Rajpoot

Automated synthesis of histology images has several potential applications in computational pathology. However, no existing method can generate realistic tissue images with a bespoke cellular layout or user-defined histo…

Image GenerationNuclear Segmentation

Cellular Segmentation and Composition in Routine Histology Images using Deep Learning

2022-03-04 · Muhammad Dawood, Raja Muhammad Saad Bashir, Srijay Deshpande, Manahil Raza 외

Identification and quantification of nuclei in colorectal cancer haematoxylin \& eosin (H\&E) stained histology images is crucial to prognosis and patient management. In computational pathology these tasks are referred t…

ManagementNuclear SegmentationPrognosisSegmentation

A Deep Learning Framework for Nuclear Segmentation and Classification in Histopathological Images

2022-03-04 · Sen yang, Jinxi Xiang, Xiyue Wang

Nucleus segmentation and classification are the prerequisites in the workflow of digital pathology processing. However, it is very challenging due to its high-level heterogeneity and wide variations. This work proposes a…

ClassificationNuclear SegmentationSegmentation

Separable-HoverNet and Instance-YOLO for Colon Nuclei Identification and Counting

2022-03-01 · Chunhui Lin, Liukun Zhang, Lijian Mao, Min Wu 외

Nuclear segmentation, classification and quantification within Haematoxylin & Eosin stained histology images enables the extraction of interpretable cell-based features that can be used in downstream explainable models i…

ClassificationExplainable ModelsNuclear SegmentationSegmentation

A Standardized Pipeline for Colon Nuclei Identification and Counting Challenge

2022-03-01 · Jijun Cheng, Xipeng Pan, Feihu Hou, Bingchao Zhao 외

Nuclear segmentation and classification is an essential step for computational pathology. TIA lab from Warwick University organized a nuclear segmentation and classification challenge (CoNIC) for H&E stained histopatholo…

ClassificationData AugmentationNuclear SegmentationSegmentation

Simultaneous Semantic and Instance Segmentation for Colon Nuclei Identification and Counting

2022-03-01 · Lihao Liu, Chenyang Hong, Angelica I. Aviles-Rivero, Carola-Bibiane Schönlieb

We address the problem of automated nuclear segmentation, classification, and quantification from Haematoxylin and Eosin stained histology images, which is of great relevance for several downstream computational patholog…

Instance SegmentationNuclear SegmentationSegmentationSemantic Segmentation

Nuclei panoptic segmentation and composition regression with multi-task deep neural networks

2022-02-23 · Satoshi Kondo, Satoshi Kasai

Nuclear segmentation, classification and quantification within Haematoxylin & Eosin stained histology images enables the extraction of interpretable cell-based features that can be used in downstream explainable models i…

DecoderExplainable ModelsMulti-Task LearningNuclear Segmentation+3
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